First Year MBBS Physiology

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Physiology Problem 5

Calculate the blood volume in an adult male given:

  • The amount of Evan’s Blue injected = 5.6 mg
  • Conc. of dye in plasma after equilibration = 0.002 mg/ml
  • Haematocrit value = 46%
  • Amount of the dye leaving the circulation during equilibration = 0.2 mg

Click on the image to enlarge

Blood volume is normal

Evan’s Blue neither leaves the vascular system nor penetrates the erythrocytes.

Radioactive iodine can be used in  place of Evan’s blue.


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