Name the graph. What are the domains on X & Y axis. Name the conditions leading to right and left shift. What is P 50?
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Given graph represents Oxygen-Haemoglobin
dissociation curve
Domains > X axis – PO2, Y axis – Hb
saturation
Conditions leading to Right
- ↓ Po2
- ↑ PCo2
- ↑ [H]+ conc.
- ↓ pH
- ↑ Body temperature
- ↑ 2,3 DPG
Conditions leading to Left
- ↑ Po2
- ↓ PCo2
- ↓ [H]+ conc.
- ↑ pH
- ↓Body temperature
- ↓2,3 DPG
P50 is the partial pressure of oxygen at
which Hb saturation with oxygen is 50%